Detailansicht
MicroRNA in Development and in the Progression of Cancer
ISBN/EAN: 9781489980649
Umbreit-Nr.: 5812260
Sprache:
Englisch
Umfang: xiii, 407 S., 9 s/w Illustr., 38 farbige Illustr.,
Format in cm:
Einband:
gebundenes Buch
Erschienen am 21.04.2014
Auflage: 1/2014
- Zusatztext
- InhaltsangabeSECTION 1: THE FUNCTIONS AND MECHANISMS OF MICRORNAs 1. miRNA biogenesis and function Abigail F. Olena and James G. Patton 2. miRNAs in cancer progression Omozusi Andrews and James G. Patton 3. MicroRNA, DNA repair and cancer Hailiang Hu SECTION 2: MICRORNAs IN STEM CELLS AND PROGRESSION OF CANCER 4. Role of microRNAs in stem cells regulation and tumorigenesis in Drosophila Lyric Forney, Stephanie Rager, Eviatar Nevo and Shree Ram Singh 5. MicroRNAs in stem cells and cancer stem cells Ryan D. Mohan, Bernadette Bibber, Garima Sinha, Shyam A. Patel, and Pranela Rameshwar 6. MicroRNAs in epithelial mesenchymal transition and breast cancer progression George R. Nahas, Bernadette M. Bibber, Pranela Rameshwar 7. MicroRNAs in the development and progression of breast cancer Muthusawamy Thangraju and Ashok Jain 8. The role of microRNAs in hematopoietic stem cells and leukemia development Safak Yalcin, Stephen S. Chung, Christopher Y. Park 9. MiRNA and chronic lymphocytic leukemia Heba Degheidy, Siddha Kasar, Chingiz Underbayev, Yao Yuan, Smruti Mehta, Marilyn Lightfoote, Gerald Marti, and Elizabeth Raveche 10. The role of miRNAs in the development of normal pancreas and pancreatic cancer, and their roles in tumor progression Yiwei Li, Dejuan Kong, Aamir Ahmad, Bin Bao, and Fazlul H. Sarkar 11. Epigenetic regulation of microRNA genes in colorectal cancer Hiromu Suzuki, Eiichiro Yamamoto, Reo Maruyama 12. MicroRNAs in the development and progression of kidney cancer Sharanjot Saini, Sumit Arora, Shahana Majid, Hiroshi Hirata and Rajvir Dahiya 13. MicroRNAs in the development and progression of skin cancer Vivek Choudhary, Meg Gullotto, Lisa Sato, and Wendy B Bollag 14. MicroRNAs in the Development and Progression of Prostate Cancer Nagalakshmi Nadiminty, Ramakumar Tummala, Allen C. Gao 15. MicroRNAs in development and progression of ovarian cancer Monika Sangwan and Neetu Dahiya SECTION 3: ROLE OF MICRORNA AND POTENTIAL CANCER THERAPEUTICS 16. MicroRNA and Cancer Drug Resistance Daohong Chen and Harikrishna Nakshatri 17. Microvesicular Transfer of microRNA in Tumor Microenvironment Krishna C Vallabhaneni, Patrice Penfornis, J. Griffin Orr, Krishna Chauhan and Radhika Pochampally 18. MicroRNA cancer therapeutics and the challenge of drug delivery Steven J. Greco, Jessian L. Munoz, Pranela Rameshwar 19. MicroRNA and Drug Delivery Joseph S. Fernandez-Moure, Jeffrey Van Epps, Bradley K. Weiner, Mauro Ferrari EnnioTasciotti
- Kurztext
- MicroRNAs (miRNAs) are small 22-nucleotides long non-coding RNAs that regulate the gene expression through translational repression and mRNA degradation in varieties of species. miRNAs play regulatory role in several fundamental biological processes from normal development to regulation of stem cells, cancer stem cells and various human diseases including cancer. miRNAs can be used as potential biomarkers for disease diagnosis and have been considered potential therapeutic strategies in cancer treatment. This is a timely and specialized book providing the current understanding of miRNAs and their potential application in cancer diagnosis, prognosis, and therapeutic strategies in cancer treatment. This book will be a valuable source of information for the scientists in the field of cancer research as well as undergraduate and graduate students who want to pursue their research careers in cancer biology.
- Autorenportrait
- Dr. Shree Ram Singh is a Staff Scientist for the Mouse Cancer Genetics Program at the National Cancer Institute. Dr. Pranela Rameshwar is a Professor of the Department of Medicine at UMDNJ-New Jersey Medical School. See attached CV for additional details.