Detailansicht
Analysis of Single-Cell Data
eBook - ODE Constrained Mixture Modeling and Approximate Bayesian Computation, BestMasters
ISBN/EAN: 9783658132347
Umbreit-Nr.: 9165245
Sprache:
Englisch
Umfang: 0 S., 4.50 MB
Format in cm:
Einband:
Keine Angabe
Erschienen am 17.03.2016
Auflage: 1/2016
E-Book
Format: PDF
DRM: Digitales Wasserzeichen
- Zusatztext
- <p>Carolin Loos introduces two novel approaches for theanalysis of single-cell data. Both approaches can be used to study cellularheterogeneity and therefore advance a holistic understanding of biologicalprocesses. The first method, ODE constrained mixture modeling, enables theidentification of subpopulation structures and sources of variability in single-cellsnapshot data. The second method estimates parameters of single-cell time-lapsedata using approximate Bayesian computation and is able to exploit the temporalcross-correlation of the data as well as lineage information.&nbsp;</p>
- Autorenportrait
- <p>Carolin Loos is currently doing her PhD at the Institute ofComputational Biology at the Helmholtz Zentrum München. She is member of thejunior research group Data-driven Computational Modeling. </p>