Detailansicht
Endolysosomal Voltage-Dependent Cation Channels
Handbook of Experimental Pharmacology 278
ISBN/EAN: 9783031315220
Umbreit-Nr.: 8897871
Sprache:
Englisch
Umfang: x, 304 S., 1 s/w Illustr., 304 p. 1 illus.
Format in cm:
Einband:
gebundenes Buch
Erschienen am 27.04.2023
Auflage: 1/2023
- Zusatztext
- This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level.
- Kurztext
- Discusses high resolution structures of endolysosomal ion channels that became available over the last few yearsPresents studies involving genetic mouse models that are utilized to derive in vivo function of these channelsHighlights functional interaction between endolysosomal membrane proteins and membrane proteins of the ER